投稿者名:tagoaika

News Release

Potential Inheritable Effects and Ethical Considerations of Epigenome Editing

November 3, 2023 Potential Inheritable Effects and Ethical Considerations of Epigenome Editing Epigenome editing is an emerging technology used to regulate gene function by controlling epigenetic states at specific locations on the genome. This method is distinct from traditional genetic editing, which involves permanently altering the DNA sequence. Notably, the intervention effects of epigenome editing are thought to be reversible, making this technology particularly attractive for its potential therapeutic applications in the treatment of genetic disorders and chronic diseases. Although some researchers argue that it presents fewer ethical issues compared with permanent genome editing, especially in terms of its impact on offspring, the potential for transgenerational epigenetic inheritance has also been reported, suggesting that epigenetic changes could be inherited across generations in mammals. This study sought to examine the ethical and practical questions of epigenome editing

News Release

Exploring the Ethics of Transplanting Human Brain Organoids into Animals

October 23, 2023 Exploring the Ethics of Transplanting Human Brain Organoids into Animals Studies using so-called “chimeric animals”, in which cells from one species are transplanted into another, have brought about a number of ethical concerns and considerations. This is especially true for research involving transplantation into animals of human brain organoids, which are three-dimensional brain tissue derived from human pluripotent stem cells. Although this area of research has seen tremendous progress over the last few years, only a few studies have examined the relevant ethical issues. A major source of controversy regards the potential for cognitive enhancement of the host animal, but a myriad of other issues remain. In light of this, the researchers have taken the proactive step of examining these issues, including some speculative issues, in order to guide future research and encourage understanding and management of the ethics of this research as developments continue. The st

1-7-1, Kagamiyama, Higashi-Hiroshima 739-8521 JAPAN

Uehiro Division for Applied Ethics
Graduate School of Humanities and Social Sciences, Hiroshima University

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