Blastocyst
Blastocyst A structure that forms at an embryonic stage approximately 6–7 days after fertilization that is capable of developing into an individual under suitable conditions. 戻る
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Brain Organoid
Brain Organoid A three-dimensional brain tissue structure created by culturing pluripotent stem cells or similar cells. Pluripotent stem cells possess self-renewal capability and the ability to differentiate into all body cell types. ES cells (derived from the inner cell mass of a blastocyst 5–7 days post-fertilization) require a donated fertilized egg, whereas iPS cells (produced by introducing multiple genes into somatic cells like blood or skin) require donated blood or skin cells. 戻る
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Broad Consent
Broad Consent Obtaining consent from a cell donor to use their donated cells for a wide range of medical and scientific research purposes. 戻る
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DNA Methylation
DNA Methylation One of the main factors constituting the epigenome. When certain sites on DNA (containing genes) become methylated, the activity of these genes can change. 戻る
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Epigenome Editing
Epigenome Editing A technique to regulate or modify gene function without altering the DNA sequence itself. This involves adjusting mechanisms such as gene on/off switches and DNA methylation in targeted regions.
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ES Cells
ES Cells Pluripotent stem cells produced by extracting the inner cell mass from a blastocyst (which can potentially develop into a fetus and eventually into a human) and culturing it in vitro. One key feature of pluripotent stem cells is their ability to differentiate into virtually all cell types that constitute the human body, a property known as pluripotency. 戻る
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Genome Editing
Genome Editing A technology used to rewrite specific DNA sequences in an organism’s genome (the entire set of genetic information) to regulate or correct gene functions. 戻る
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International Society for Stem Cell Research (ISSCR)
International Society for Stem Cell Research (ISSCR) The world’s largest academic organization in the field of stem cell research. 戻る